43North is an accelerator program based in Buffalo, New York, dedicated to fostering high-growth companies by investing $5 million annually. Since its inception in 2014, 43North has been instrumental in revitalizing Buffalo's startup ecosystem, offering substantial funding and resources to attract innovative businesses to the region. The program culminates in the annual 43North Finals, a public event where five companies are awarded $1 million each, securing a spot in the next accelerator cohort.

This initiative has led to the emergence of successful ventures, including a unicorn and publicly traded companies, and has attracted co-investors such as Bessemer, Iconiq Capital, and Rise of the Rest. Supported by sponsors like New York State, Empire State Development, and the Ralph C. Wilson, Jr.

Foundation, 43North continues to play a pivotal role in Buffalo's economic development by nurturing a diverse, industry-agnostic portfolio of startups.