BioTech Investors & Venture Capital firms in 2025

Our complete guide in 2025 for the top investors and VC firms in BioTech.

Contributors: Carl Lager

Last updated: April 21, 2025

BioTech Investors & Venture Capital firms in 2025BioTech Investors & Venture Capital firms in 2025

The Biotech Startup Surge: Strong Investment Growth in 2024

Biotech startups experienced a powerful resurgence in 2024, reversing the slowdown seen in 2022 and 2023. Across the U.S. and Europe, biotech companies raised $28.1 billion in venture capital—up 33% from $21.2 billion the previous year. This surge came with fewer deals but larger average check sizes, as investors gravitated toward fewer, higher-conviction bets.

One of the most notable shifts was in first-time biotech financings. New startups raised $7.7 billion across 137 deals, more than doubling the $3.8 billion seen in 2023. Investors are fueling larger seed and Series A rounds early, setting the stage for rapid scale and clinical progress. In fact, seven early-stage biotech startups raised over $300 million—previously a rarity in the space.

Beyond core life sciences, funding flowed into fast-emerging fields like AI-driven drug discovery, computational biology, and synthetic biology. The intersection of biotech and AI is rapidly expanding, pulling in capital from both traditional life sciences firms and tech-native VCs.

logos of the major venture capital firms within biotechlogos of the major venture capital firms within biotech

Top Biotech Venture Capital Firms Driving Growth

Biotech continues to be dominated by deep-domain specialists. Firms such as Novo Holdings, Frazier Life Sciences, Arch Venture Partners, and Forbion Ventures led some of the biggest biotech deals in 2024. These investors bring scientific expertise and long-term vision to early-stage drug development and therapeutic innovation.

Corporate venture capital also gained ground. Pharmaceutical giants like Bristol Myers Squibb, Sanofi, Eli Lilly, and Merck ramped up their VC activity to gain early exposure to next-gen drug pipelines. These strategic investments offer a dual win: financial returns and pipeline acceleration.

Tech VCs Enter Biotech

In a growing crossover trend, prominent Silicon Valley VCs are venturing into biotech. Andreessen Horowitz’s Bio Fund and SoftBank led major biotech rounds in 2024, with a clear focus on computational biology. For example, a16z backed Genesis Therapeutics, a startup using AI to speed up drug development. This convergence of biotech and deep tech is reshaping the investor landscape.

Biotech Startups to Watch in 2025

Some of the largest biotech rounds ever recorded happened in 2024. Xaira Therapeutics raised $1 billion in launch funding, signaling enormous confidence in its scientific platform. Meanwhile, Seaport Therapeutics and Exsilio Therapeutics, both led by repeat biotech founders, secured Series A rounds north of $100–200 million.

Experienced Founders Are in High Demand

VCs are placing big bets on veteran biotech entrepreneurs. The track record of success is translating into higher valuations and more aggressive financing strategies, allowing these companies to move swiftly toward clinical development.

Clinical-Stage Startups Still Attract Late-Stage Capital

While early-stage biotech drew much attention, mid-stage companies didn’t miss out. Neumora Therapeutics raised a $250 million Series B, while Ascend Elements—a cleantech-adjacent biotech startup—closed a $300 million Series D, reinforcing confidence in clinical and commercial progress.

Outlook for Biotech IPOs and Exits in 2025

Although the IPO market has yet to recover to its 2020–21 highs, sentiment is shifting. Several biotech startups are expected to go public in 2025, with VCs and corporates alike eyeing M&A opportunities and strategic exits.

With AI now fully embedded in drug discovery, and traditional pharma embracing early-stage innovation, the biotech investment boom is expected to continue well into 2025.

All Leading Investors & Venture Capital Firms in BioTech

Our complete list of all active venture capital firms and investors investing in BioTech.

10Branch
Founded
2015
Investments
5
Exits
2
Investment stage
Series B
Series C
Company profile
See full breakdown
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111° West Capital
Founded
2021
Investments
3
Exits
0
Investment stage
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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2150
Founded
2020
Investments
8
Exits
0
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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4BIO Capital
Founded
2014
Investments
13
Exits
5
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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500 Startups
Founded
2010
Investments
2802
Exits
337
Investment stage
Seed
Series A
Series B
Company profile
See full breakdown
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5AM Ventures
Founded
2002
Investments
166
Exits
42
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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7wire Ventures
Founded
2011
Investments
56
Exits
4
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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A* Capital
Founded
2021
Investments
23
Exits
0
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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ABRY Partners
Founded
1989
Investments
85
Exits
42
Investment stage
Seed
Series A
Series B
Company profile
See full breakdown
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AME Cloud Ventures
Founded
2012
Investments
274
Exits
63
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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AbCellera Biologics
Founded
2012
Investments
2
Exits
0
Investment stage
Series B
Series C
Series D
Company profile
See full breakdown
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AbbVie
Founded
2013
Investments
9
Exits
2
Investment stage
Series C
Series D
Series B
Company profile
See full breakdown
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Abingworth
Founded
1973
Investments
166
Exits
78
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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Able Partners
Founded
2016
Investments
62
Exits
5
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Acequia Capital (AceCap)
Founded
2010
Investments
433
Exits
41
Investment stage
Seed
Series A
Series B
Company profile
See full breakdown
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Acre Venture Partners
Founded
2016
Investments
32
Exits
1
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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Adage Capital Management
Founded
2001
Investments
87
Exits
55
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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Adams Street Partners
Founded
1972
Investments
226
Exits
85
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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Ag Startup Engine
Founded
2015
Investments
23
Exits
0
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Agilent Technologies
Founded
1999
Investments
32
Exits
8
Investment stage
Series B
Series C
Company profile
See full breakdown
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Airbus Ventures
Founded
2015
Investments
64
Exits
8
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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AllianceBernstein
Founded
1967
Investments
47
Exits
21
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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Ally Bridge Group
Founded
2013
Investments
67
Exits
27
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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Alpha Edison
Founded
2016
Investments
93
Exits
4
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Altimeter Capital
Founded
2008
Investments
87
Exits
20
Investment stage
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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Ananda Impact Ventures
Founded
2010
Investments
52
Exits
4
Investment stage
Seed
Series A
Company profile
See full breakdown
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Andera Partners
Founded
1953
Investments
173
Exits
52
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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Andreessen Horowitz
Founded
2009
Investments
1231
Exits
191
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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AngelMD
Founded
2013
Investments
14
Exits
0
Investment stage
Seed
Series A
Series B
Company profile
See full breakdown
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Anterra Capital
Founded
2013
Investments
26
Exits
2
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
View VC Firm
Aperture Venture Partners
Founded
2002
Investments
53
Exits
23
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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Arboretum Ventures
Founded
2002
Investments
90
Exits
24
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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Artis Ventures (AV)
Founded
2001
Investments
101
Exits
27
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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Astanor Ventures
Founded
2017
Investments
41
Exits
1
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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Asymmetry Ventures
Founded
1899
Investments
187
Exits
2
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Atlas Venture
Founded
1980
Investments
569
Exits
171
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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Autism Impact Fund
Founded
Investments
8
Exits
0
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Avalon Ventures
Founded
1983
Investments
181
Exits
49
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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BBG Ventures
Founded
2014
Investments
100
Exits
9
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Baillie Gifford
Founded
1908
Investments
148
Exits
39
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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Baird Capital
Founded
2019
Investments
163
Exits
45
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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Baltic Sandbox Ventures
Founded
2018
Investments
18
Exits
Investment stage
Pre-Seed
Seed
Company profile
See full breakdown
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Barclays
Founded
2018
Investments
9
Exits
1
Investment stage
Series A
Series B
Series C
Series D
Company profile
See full breakdown
View VC Firm
Bayern Capital
Founded
2011
Investments
78
Exits
12
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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BeiGene
Founded
2010
Investments
4
Exits
1
Investment stage
Series A
Series B
Company profile
See full breakdown
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Bessemer Venture Partners
Founded
2011
Investments
1257
Exits
281
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
View VC Firm
Bienville Capital
Founded
2008
Investments
64
Exits
7
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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Big Idea Ventures
Founded
2018
Investments
72
Exits
2
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Bill & Melinda Gates Foundation
Founded
1997
Investments
199
Exits
45
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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BlueYard Capital
Founded
2016
Investments
47
Exits
0
Investment stage
Seed
Series A
Series B
Company profile
See full breakdown
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Bolt
Founded
2013
Investments
105
Exits
13
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Boro Capital
Founded
2017
Investments
22
Exits
2
Investment stage
Pre-Seed
Seed
Company profile
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BoxGroup
Founded
2009
Investments
559
Exits
103
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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Breakout Ventures
Founded
2016
Investments
24
Exits
2
Investment stage
Seed
Series A
Company profile
See full breakdown
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Breyer Capital
Founded
2006
Investments
124
Exits
12
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Builders VC
Founded
2018
Investments
58
Exits
7
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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CRV
Founded
1970
Investments
620
Exits
152
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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Caffeinated Capital
Founded
2009
Investments
126
Exits
8
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Cambridge Innovation Capital
Founded
2013
Investments
71
Exits
4
Investment stage
Seed
Series A
Series B
Company profile
See full breakdown
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Canaan Partners
Founded
1987
Investments
731
Exits
147
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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Cantos
Founded
2016
Investments
81
Exits
5
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Capnamic Ventures
Founded
2012
Investments
93
Exits
8
Investment stage
Seed
Series A
Series B
Company profile
See full breakdown
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Capricorn Partners
Founded
1993
Investments
87
Exits
23
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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Catalio Capital Management
Founded
2016
Investments
35
Exits
5
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Celesta Capital
Founded
2019
Investments
136
Exits
8
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Climentum Capital
Founded
2021
Investments
11
Exits
0
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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CoCoon Ignite Ventures
Founded
2016
Investments
16
Exits
2
Investment stage
Seed
Series A
Series B
Company profile
See full breakdown
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Coatue
Founded
1999
Investments
366
Exits
38
Investment stage
Pre-Seed
Seed
Series A
Series B
Series D
Company profile
See full breakdown
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Coinbase Ventures
Founded
2018
Investments
264
Exits
7
Investment stage
Seed
Series A
Series B
Company profile
See full breakdown
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Connectivity Ventures Fund
Founded
2015
Investments
19
Exits
5
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Conscience VC
Founded
2020
Investments
4
Exits
0
Investment stage
Seed
Series A
Series B
Company profile
See full breakdown
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Cove Fund
Founded
2014
Investments
31
Exits
0
Investment stage
Seed
Company profile
See full breakdown
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Crescent Fund
Founded
2021
Investments
Exits
0
Investment stage
Seed
Series A
Series B
Company profile
See full breakdown
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DCVC
Founded
2011
Investments
452
Exits
95
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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DNA Capital
Founded
2013
Investments
28
Exits
2
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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Decheng Capital
Founded
2012
Investments
71
Exits
15
Investment stage
Seed
Company profile
See full breakdown
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Declaration Partners
Founded
2017
Investments
28
Exits
1
Investment stage
Series A
Series B
Series C
Company profile
See full breakdown
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Digitalis Ventures
Founded
2016
Investments
48
Exits
0
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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Domain Associates
Founded
1985
Investments
303
Exits
90
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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Dreamers VC
Founded
2018
Investments
40
Exits
5
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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EDBI
Founded
1991
Investments
155
Exits
44
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
View VC Firm
Eagle Venture Fund
Founded
Investments
6
Exits
0
Investment stage
Series C
Company profile
See full breakdown
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Eclipse Ventures
Founded
2015
Investments
108
Exits
11
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
View VC Firm
Elm Street Ventures
Founded
2006
Investments
24
Exits
7
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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Embryo Ventures
Founded
2019
Investments
10
Exits
0
Investment stage
Pre-Seed
Seed
Company profile
See full breakdown
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Exsight Ventures
Founded
2015
Investments
9
Exits
1
Investment stage
Pre-Seed
Seed
Series A
Series B
Company profile
See full breakdown
View VC Firm
F-Prime Capital
Founded
1946
Investments
366
Exits
78
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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Felicis Ventures
Founded
2006
Investments
556
Exits
152
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Fifty Years
Founded
2015
Investments
113
Exits
5
Investment stage
Seed
Company profile
See full breakdown
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First Round Capital
Founded
2004
Investments
847
Exits
189
Investment stage
Seed
Company profile
See full breakdown
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First Star Ventures
Founded
2014
Investments
38
Exits
5
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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First Venture
Founded
2017
Investments
18
Exits
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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FirstMark
Founded
2008
Investments
333
Exits
52
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
View VC Firm
Flagship Pioneering
Founded
2000
Investments
256
Exits
66
Investment stage
Pre-Seed
Seed
Series A
Series B
Series C
Company profile
See full breakdown
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Flare Capital Partners
Founded
2015
Investments
60
Exits
9
Investment stage
Seed
Series A
Series C
Series D
Series B
Company profile
See full breakdown
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Flatiron Venture Partners
Founded
2017
Investments
2
Exits
0
Investment stage
Seed
Series A
Company profile
See full breakdown
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Floodgate
Founded
2006
Investments
351
Exits
90
Investment stage
Pre-Seed
Seed
Series A
Company profile
See full breakdown
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Fly Ventures
Founded
2016
Investments
83
Exits
5
Investment stage
Pre-Seed
Seed
Company profile
See full breakdown
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Foresite Capital
Founded
2011
Investments
135
Exits
53
Investment stage
Seed
Series A
Series B
Series C
Series D
Company profile
See full breakdown
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Formation Venture Engineering
Founded
2018
Investments
Exits
0
Investment stage
Pre-Seed
Company profile
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What factors should biotech startups consider when choosing investors?

Biotech startups should consider several factors when choosing investors, including the investor's industry expertise, the level of support provided, their track record with similar companies, and their alignment with the startup's values and goals. Finding investors who offer not just financial resources but also strategic guidance and networking opportunities can be crucial for the growth and success of the company.

What is sustainable and ethical investment in BioTech?

Sustainable and ethical investment in biotech focuses on investments that consider not just financial returns but also the broader impact on society and the environment. This includes promoting practices that are environmentally sustainable, socially responsible, and ethically sound. Startups that prioritize these values are more likely to attract investors who are committed to making a positive difference.

Who are some of the key investors in the BioTech industry?

Some key investors in the biotech industry include Arch Venture Partners, Flagship Pioneering, Third Rock Ventures, and Sofinnova Partners. These investors are known for their significant contributions to supporting innovative biotech ventures and helping startups achieve their goals.