Ascend Venture Capital is a venture capital firm based in St. Louis, Missouri, specializing in data-centric investments that aim to revolutionize industries. Their investment approach focuses on companies with active prototypes, the potential for significant growth, and the ability to achieve exceptional outcomes.

They emphasize themes such as first movers, network effects, persistent trends, data-centric transitions, and supply-inhibited ecosystems. Ascend's strategy includes partnering with preeminent capital partners, milestone-based investing, providing operational guidance, and being flexible in their investment approach, whether leading or following. Their portfolio comprises companies like Accumulate Network, Applied Bioplastics, Arbol Market, Astrapi Corp, Boat Planet, Cased, FreightWaves, Journey Foods, Kroo, Metasoul, Oxio, Producers Trust, Refashiond, Sojourn AI, StoryFit, and Utopia Labs.

The firm is located at 4220 Duncan Avenue, Suite 201, St. Louis, MO, 63110, United States.