Base10 Partners is a San Francisco-based venture capital firm founded in 2017 by Adeyemi Ajao and TJ Nahigian. The firm specializes in early-stage investments, focusing on automating traditional sectors of the economy, including transportation, healthcare, retail, logistics, and construction. Base10 employs a data-driven approach to identify and invest in companies that are implementing fundamental automation technologies within these industries.

Notable portfolio companies include Notion, Figma, Stripe, Wealthsimple, SecureFrame, Todyl, and Riot. In 2021, Base10 launched The Advancement Initiative, a growth-stage fund that donates 50% of its profits to Historically Black Colleges and Universities (HBCUs) to support scholarships and university endowments. This initiative underscores the firm's commitment to diversity and inclusion within the tech industry.

As of April 2022, Base10 Partners has raised over $1 billion in assets under management, making it the first Black-led venture capital firm to reach this milestone.