Khosla Ventures is a private American venture capital firm based in Menlo Park, California, founded in 2004 by Vinod Khosla, a former general partner at Kleiner Perkins. The firm focuses on early-stage investments across various sectors, including internet, computing, mobile technology, artificial intelligence, financial services, agriculture, healthcare, and clean technology. Khosla Ventures is renowned for its bold approach, often making significant investments in groundbreaking technologies and companies.

Notable portfolio companies include Impossible Foods, Instacart, Affirm, DoorDash, Square, and OpenAI. The firm's investment philosophy emphasizes high-, high-reward opportunities, particularly in areas like green technology and artificial intelligence. For instance, Khosla Ventures has invested in Commonwealth Fusion Systems, aiming to develop fusion power, and in startups like Quaise and Mazama Energy, focusing on superhot geothermal energy.

The firm has also been a significant backer of OpenAI, with Vinod Khosla expressing strong support for the company's leadership and vision. Khosla Ventures operates with a philosophy that values "brutal honesty over hypocritical politeness," fostering a culture of direct and transparent communication.