Lightstone Ventures

2012

Founded

54

Investments

United States

Offices

Venture Fund

Investor Type

About

Lightstone Ventures is a venture capital firm founded in 2012, specializing in the biopharmaceutical and medical device sectors. With nearly 100 years of combined operational experience, the firm has been instrumental in the development of numerous healthcare companies, contributing to 20 IPOs and 19 acquisitions. Their investment approach is centered on partnering with visionary founders to translate novel scientific breakthroughs into clinically and commercially meaningful therapies.

Lightstone Ventures focuses on all stages of company growth, offering both financial backing and hands-on guidance to navigate day-to-day operations. Their global presence, with offices in the U.S. and Ireland, enables them to build networks with international strategic and financial partners, exploring diverse development and commercialization strategies.

The firm's portfolio includes notable companies such as Acceleron Pharma, ALX Oncology, Calithera BioSciences, and MicroVention, reflecting their commitment to impactful medical innovations.

Portfolio Companies

Acceleron Pharma, ALX Oncology, Calithera BioSciences, MicroVention, Nimbus, Plexxikon, Portola Pharmaceuticals, Promedior, Proteolix, Ra Pharma

Gepgraphic Focus

United States, Ireland

Key Differentiators

Nearly 100 years of combined operational experience, Involvement in 20 IPOs and 19 acquisitions, Global presence with offices in the U.S. and Ireland, Hands-on partnership with founders across all company growth stages

Thypical Investment Size

Not publicly disclosed

Total Funds Raised

Not publicly disclosed

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Software

SaaS

Consumer

FinTech

Menlo Park

Pre-Seed

Seed

Series A

United States