Pillar VC is a Boston-based venture capital firm founded in 2016, dedicated to supporting early-stage companies in sectors such as biotech, crypto, deep enterprise SaaS, healthcare, and university spinouts. The firm focuses on backing founders from the inception of their ideas, assisting in moving concepts to real-world applications. Pillar VC emphasizes a collaborative approach, offering capital, connections, recruitment support, and CEO coaching to foster the growth of its portfolio companies.

The firm's investment philosophy centers on building "pillar" companies that become foundational to the economy, with a strong presence in Boston and the Northeast. Notable portfolio companies include Jellyfish, VideaHealth, Kula Bio, Neural Magic, Asimov, Abridge, Refraction AI, Zapata Computing, Cake, Kite, Higharc, and JobGet.