Sica Ventures is an early-stage venture capital firm founded in 2019, headquartered in Columbus, Ohio. The firm specializes in providing seed capital to innovative technology startups, focusing on sectors such as aerospace, defense, biotechnology, communications, networking, software, advanced manufacturing, agriculture technology, artificial intelligence, machine learning, autonomous vehicles, and big data. Sica Ventures aims to support the growth of emerging companies by investing in areas that drive technological advancement and innovation.

The firm's mission is to support the advancement of science, technology, and innovation for the betterment of all, with a vision of a future with less suffering, greater technologies, and peace. Their goal is to bring the resources and support needed to make a significant positive impact on the trajectory of mankind. The partners include Dominick Sica, Managing Partner, and Vinny Sica, General Partner & Principal.

Sica Ventures has a local reach in Columbus, Ohio, and the DMV area (Washington DC, Maryland, Virginia).