Thomas, McNerney & Partners is a healthcare venture capital and private equity firm specializing in life sciences and medical technology investments across all stages of development. Established in 2001 by James E. Thomas and Peter H.

McNerney, the firm is headquartered in Stamford, Connecticut, with additional offices in Minneapolis, Minnesota, and San Francisco, California. The team comprises professionals with extensive experience in healthcare operations and venture capital, including co-founders who previously led healthcare investments at Coral Ventures and Warburg Pincus. The firm's investment focus spans the pharmaceutical, medical device, biotechnology, and diagnostic sectors, as well as other areas leveraging medical technology innovation.

They provide growth capital to emerging companies, assist in spinning out products and divisions from major medical device and pharmaceutical companies, and participate in structured financings and recapitalizations. As of 2019, Thomas, McNerney & Partners had made 46 investments, led 16 investments, and achieved 15 exits, with notable investments including Invitae, VertiFlex, Torax Medical, Auspex Pharmaceuticals, Zogenix, CAS Medical Systems, Celator Pharmaceuticals, Virdante Pharmaceuticals, Elron Electronic Industries, aSGB, and Tioga Pharmaceuticals.