Two Sigma Ventures is an early-stage venture capital firm based in New York City, established in 2012. The firm focuses on investing in transformative companies that leverage data science and advanced engineering to drive innovation across various industries. With a team comprising data scientists, engineers, and industry experts, Two Sigma Ventures provides extensive support to its portfolio companies, offering access to a proprietary network of over 1,600 data scientists, engineers, and other industry experts.

The firm's investment strategy emphasizes early-stage investments, typically from seed to Series B rounds, and spans a wide range of sectors, including enterprise and consumer software, AI-powered applications, infrastructure and developer tools, and data-driven biotech and healthcare. Two Sigma Ventures has a history of successful investments, including companies like Recursion Pharmaceuticals, CoverWallet, Carbon Health, WHOOP, and insitro. The firm's approach combines rigorous data science, product and engineering expertise, and talent and leadership development to support the growth of its portfolio companies.