U.S. Venture Partners (USVP) is a prominent Silicon Valley venture capital firm specializing in early-stage investments across sectors such as cybersecurity, enterprise software, consumer internet, mobile, e-commerce, healthcare, and IT-enabled healthcare services. Established in 1981 by Bill Bowes, Stuart Moldaw, and Robert Sackman, USVP has a rich history of supporting innovative companies.

Over the past four decades, the firm has invested over $4.4 billion in 529 companies, with 93 achieving initial public offerings (IPOs).

USVP's investment strategy focuses on leading Series A and B rounds, typically investing between $5 million and $10 million in companies with revenue potential exceeding $1 billion. The firm emphasizes sectors where it has deep domain expertise, including cybersecurity, enterprise software, consumer internet, mobile, e-commerce, healthcare, and IT-enabled healthcare services.

The firm's team comprises former entrepreneurs, technologists, corporate executives, and financial professionals who assist portfolio companies with strategy, scaling, team building, product development, and business development. Notable investments include Box, Cato Networks, Epsagon, Happy Returns, HotelTonight, Human Interest, Imperva, Inari Medical, Inspire Medical Systems, Intersect ENT, Kenna, Medigate, Omada Health, Pluto TV, ThreatMetrix, Trunk Club, Trusteer, and Yammer.

In December 2022, USVP closed its thirteenth fund, USVP XIII, raising $400 million to continue its focus on early-stage investments in cybersecurity, enterprise software, consumer, and healthcare sectors.

USVP's approach combines deep industry knowledge with a collaborative partnership model, aiming to build market leaders and deliver strong returns for its investors.