Vine St. Ventures is a venture capital firm based in Cincinnati, Ohio, specializing in early-stage investments in internet and mobile businesses across the United States. Established in 2012, the firm focuses on sectors such as e-commerce, internet, software, mobile, marketing automation, SaaS, apps, enterprise software, social media, and travel.

Vine St. Ventures has a history of investing in companies like Losant, Terminus, and Ahalogy. The firm typically participates in funding rounds with an average size of $3 million and has been involved in 21 investments, with 4 successful exits.